San Francisco 49ers at Indianapolis Colts
· National Football League
How can I watch 49ers vs. Colts?
- TV Channel: 49ers at Colts 2021-22 NFL, week 16 is broadcasted nationally on ESPN.
- Online streaming: Sign up for Fubo.
In Canada, viewers can watch 49ers vs. Colts on DAZN.
Statistics
 SF |
 IND |
|
|---|---|---|
| 20.7 | Points Per Game | 33.1 |
| 379.6 | Total Yards | 387.1 |
| 284.3 | Yards Passing | 257.0 |
| 95.3 | Yards Rushing | 130.1 |
| 19.7 | Points Allowed Per Game | 20.0 |
| 326.0 | Yards Allowed | 363.7 |
| 225.1 | Pass Yards Allowed | 273.4 |
| 100.9 | Rush Yards Allowed | 90.3 |
Indianapolis Colts Injuries
| NAME, POS | STATUS | DATE |
|---|---|---|
| Tyler Goodson, RB | Questionable | Oct 21 |
| Josh Downs, WR | Questionable | Oct 21 |
| Ashton Dulin, WR | Questionable | Oct 21 |
| Samson Ebukam, DE | Questionable | Oct 20 |
| Tyquan Lewis, DE | Questionable | Oct 19 |
San Francisco 49ers Injuries
| NAME, POS | STATUS | DATE |
|---|---|---|
| Upton Stout, CB | Questionable | Oct 21 |
| Brock Purdy, QB | Questionable | Oct 21 |
| Ricky Pearsall, WR | Questionable | Oct 21 |
| Yetur Gross-Matos, DE | Questionable | Oct 21 |
| Jake Brendel, C | Questionable | Oct 20 |
Game Information
Lucas Oil Stadium
Location: Indianapolis, IN
Capacity:
2025 NFC West Standings
| TEAM | W | L | PCT | T | PF | PA |
|---|---|---|---|---|---|---|
| San Francisco | 2 | 138 | 145 | 0 | .714 | 5 |
| Seattle | 2 | 136 | 193 | 0 | .714 | 5 |
| Los Angeles | 2 | 117 | 175 | 0 | .714 | 5 |
| Arizona | 5 | 154 | 153 | 0 | .286 | 2 |
2025 AFC South Standings
| TEAM | W | L | PCT | T | PF | PA |
|---|---|---|---|---|---|---|
| Indianapolis | 1 | 140 | 232 | 0 | .857 | 6 |
| Jacksonville | 3 | 155 | 146 | 0 | .571 | 4 |
| Houston | 4 | 88 | 127 | 0 | .333 | 2 |
| Tennessee | 6 | 192 | 96 | 0 | .143 | 1 |
49ers Last 5
| Date | OPP | Result |
|---|---|---|
vs  ARI |
W 16-15 | |
vs  JAX |
L 26-21 | |
@  LAR |
W 26-23 OT | |
@  TB |
L 30-19 | |
vs  ATL |
W 20-10 |
TEN
LV
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